Treatment - Anaphylactic Transfusion Reactions

The transfusion must be immediately stopped and under no circumstances should it be restarted. The attending physician must be notified STAT.

The reaction is managed in the same way as a severe allergic reaction to other allergens (fluids, epinephrine, antihistimines, bronchodilators, vasopressors as appropriate).

Patients experiencing these symptoms should be closely monitored for at least six hours after onset of symptoms.

If possible, further transfusions should not be given until the transfusion service has completed its serologic investigation and determined the cause of the reaction.