Treatment of Acute Hemolytic Transfusion Reactions (immune)

Treatment varies with the clinical condition of each patient and focuses on providing cardiovascular support with IV fluids and vasopressors.

Note, however, that care should be taken to avoid fluid overload in patients with impaired cardiac or renal function.

If present, disseminated Intravascular hemolysis (DIC) and hypotension must be treated early to limit renal damage.

If possible, further transfusions should not be given until the transfusion service has completed its serologic investigation and determined the cause of the reaction.