CBS R&D-sponsored symposium on Transfusion Immunology and Related Topics. This one-day symposium will be held on September 8, 2012 at the University of Toronto.
IgA Deficiency
IgA deficiency is the most common human immunodeficiency. Although the majority of IgA deficient individuals are asymptomatic, some IgA deficient individuals have a higher prevalence of respiratory and gastrointestinal tract infections. From a transfusion medicine perspective, the presence of anti-IgA in an IgA deficient recipient is a possible cause of anaphylactic transfusion reactions. Approximately 20% of anaphylactic transfusion reactions in a Caucasian population may be associated with anti-IgA in IgA deficient recipients1.
